- The Bishkek — Osh highway at sections 121–138 km (Too-Ashuu pass) and 198–265 km (Chychkan gorge, Ala-Bel pass);
- The Suusamyr — Talas — Taraz highway at 1–14 km (Otmok pass);
- The Myrza-Ake — Kara-Kuldja — Alaykuu highway at 55–115 km;
- The Ala-Buka — Kanysh-Kiya highway at 45–112 km (Chapchyma pass);
- The Krasnaya Gorka — Akhtash highway at 0–3 km;
- The Sary-Tash — Daroot-Korgon — Karamyk highway at 97–98 km;
- The Bishkek — Naryn — Torugart highway at 292–305 km (Dolon pass);
- The Aral — Min-Kush highway at 1–14 km;
- The Aral — Suusamyr highway at 8–21 km;
- The Balikchi — Kazarman — Manas highway at 326–349 km (Kok-Art pass);
- The Karakol — Enilchek highway at 45–90 km (Chon-Ashuu pass).
Road conditions may be dangerous: there is a possibility of ice formation and slippery surfaces on the roads. It is important to maintain a safe distance between vehicles, which should be at least 500 meters.