During the study, the medical records of 130 patients were analyzed using statistical methods such as the Mann-Whitney U test, χ², and the calculation of relative odds using StatTech v.4.8.7 software.
It was found that polypharmacy is observed in almost half of the studied patients (48.5%), and it has a significant correlation with late-stage cancer (54% vs. 20.9%), the appointment of palliative treatment (76.2% compared to 46.3%), and frequent interruptions in the therapeutic process (65.1% compared to 20.9%; odds ratio = 7). Such patients exhibit more pronounced comorbidity, although echocardiographic studies are conducted less frequently (65.1% vs. 80.6%).
The authors of the article emphasize that polypharmacy is an indicator of a complex clinical condition. This underscores the need for the development of optimized algorithms for managing such patients, enhancing cardiomonitoring, and mandatory echocardiography during examinations to improve treatment safety.
This study highlights the importance of a comprehensive approach to the therapy of cancer patients with cardiovascular diseases and the necessity of integrating cardiological monitoring into standard clinical protocols.
